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Loss of Fbw7 Reprograms Adult Pancreatic Ductal Cells into α, δ, and β Cells
The adult pancreas is capable of limited regeneration after injury but has no defined stem cell population. The cell types and molecular signals that govern the production of new pancreatic tissue are not well understood. Here, we show that inactivation of the SCF-type E3 ubiquitin ligase substrate...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136739/ https://www.ncbi.nlm.nih.gov/pubmed/25105579 http://dx.doi.org/10.1016/j.stem.2014.06.019 |