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Influence of Metal of the Applicator on the Dose Distribution during Brachytherapy

This study explores how the metal materials of the applicator influence the dose distribution when performing brachytherapy for cervical cancer. A pinpoint ionization chamber, Monte Carlo code MCNPX, and treatment planning system are used to evaluate the dose distribution for a single Ir-192 source...

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Autores principales: Wu, Chin-Hui, Shiau, An-Cheng, Liao, Yi-Jen, Lin, Hsin-Yu, Liu, Yen-Wan Hsueh, Hsu, Shih-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136780/
https://www.ncbi.nlm.nih.gov/pubmed/25133789
http://dx.doi.org/10.1371/journal.pone.0104831
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author Wu, Chin-Hui
Shiau, An-Cheng
Liao, Yi-Jen
Lin, Hsin-Yu
Liu, Yen-Wan Hsueh
Hsu, Shih-Ming
author_facet Wu, Chin-Hui
Shiau, An-Cheng
Liao, Yi-Jen
Lin, Hsin-Yu
Liu, Yen-Wan Hsueh
Hsu, Shih-Ming
author_sort Wu, Chin-Hui
collection PubMed
description This study explores how the metal materials of the applicator influence the dose distribution when performing brachytherapy for cervical cancer. A pinpoint ionization chamber, Monte Carlo code MCNPX, and treatment planning system are used to evaluate the dose distribution for a single Ir-192 source positioned in the tandem and ovoid. For dose distribution in water with the presence of the tandem, differences among measurement, MCNPX calculation and treatment planning system results are <5%. For dose distribution in water with the presence of the ovoid, the MCNPX result agrees with the measurement. But the doses calculated from treatment planning system are overestimated by up to a factor of 4. This is due to the shielding effect of the metal materials in the applicator not being considered in the treatment planning system. This result suggests that the treatment planning system should take into account corrections for the metal materials of the applicator in order to improve the accuracy of the radiation dose delivered.
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spelling pubmed-41367802014-08-20 Influence of Metal of the Applicator on the Dose Distribution during Brachytherapy Wu, Chin-Hui Shiau, An-Cheng Liao, Yi-Jen Lin, Hsin-Yu Liu, Yen-Wan Hsueh Hsu, Shih-Ming PLoS One Research Article This study explores how the metal materials of the applicator influence the dose distribution when performing brachytherapy for cervical cancer. A pinpoint ionization chamber, Monte Carlo code MCNPX, and treatment planning system are used to evaluate the dose distribution for a single Ir-192 source positioned in the tandem and ovoid. For dose distribution in water with the presence of the tandem, differences among measurement, MCNPX calculation and treatment planning system results are <5%. For dose distribution in water with the presence of the ovoid, the MCNPX result agrees with the measurement. But the doses calculated from treatment planning system are overestimated by up to a factor of 4. This is due to the shielding effect of the metal materials in the applicator not being considered in the treatment planning system. This result suggests that the treatment planning system should take into account corrections for the metal materials of the applicator in order to improve the accuracy of the radiation dose delivered. Public Library of Science 2014-08-18 /pmc/articles/PMC4136780/ /pubmed/25133789 http://dx.doi.org/10.1371/journal.pone.0104831 Text en © 2014 Wu et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Wu, Chin-Hui
Shiau, An-Cheng
Liao, Yi-Jen
Lin, Hsin-Yu
Liu, Yen-Wan Hsueh
Hsu, Shih-Ming
Influence of Metal of the Applicator on the Dose Distribution during Brachytherapy
title Influence of Metal of the Applicator on the Dose Distribution during Brachytherapy
title_full Influence of Metal of the Applicator on the Dose Distribution during Brachytherapy
title_fullStr Influence of Metal of the Applicator on the Dose Distribution during Brachytherapy
title_full_unstemmed Influence of Metal of the Applicator on the Dose Distribution during Brachytherapy
title_short Influence of Metal of the Applicator on the Dose Distribution during Brachytherapy
title_sort influence of metal of the applicator on the dose distribution during brachytherapy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136780/
https://www.ncbi.nlm.nih.gov/pubmed/25133789
http://dx.doi.org/10.1371/journal.pone.0104831
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