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A Role for the Vacuolating Cytotoxin, VacA, in Colonization and Helicobacter pylori–Induced Metaplasia in the Stomach
Carriage of Helicobacter pylori strains producing more active (s1/i1) forms of VacA is strongly associated with gastric adenocarcinoma. To our knowledge, we are the first to determine effects of different polymorphic forms of VacA on inflammation and metaplasia in the mouse stomach. Bacteria produci...
Autores principales: | Winter, Jody A., Letley, Darren P., Cook, Katherine W., Rhead, Joanne L., Zaitoun, Abed A. M., Ingram, Richard J. M., Amilon, Karin R., Croxall, Nicola J., Kaye, Phillip V., Robinson, Karen, Atherton, John C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136800/ https://www.ncbi.nlm.nih.gov/pubmed/24625807 http://dx.doi.org/10.1093/infdis/jiu154 |
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