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Novel Mechanisms of Sildenafil in Pulmonary Hypertension Involving Cytokines/Chemokines, MAP Kinases and Akt

Pulmonary arterial hypertension (PH) is associated with high mortality due to right ventricular failure and hypoxia, therefore to understand the mechanism by which pulmonary vascular remodeling initiates these processes is very important. We used a well-characterized monocrotaline (MCT)-induced rat...

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Detalles Bibliográficos
Autores principales: Kiss, Tamas, Kovacs, Krisztina, Komocsi, Andras, Tornyos, Adrienn, Zalan, Petra, Sumegi, Balazs, Gallyas, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136836/
https://www.ncbi.nlm.nih.gov/pubmed/25133539
http://dx.doi.org/10.1371/journal.pone.0104890