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Novel Mechanisms of Sildenafil in Pulmonary Hypertension Involving Cytokines/Chemokines, MAP Kinases and Akt
Pulmonary arterial hypertension (PH) is associated with high mortality due to right ventricular failure and hypoxia, therefore to understand the mechanism by which pulmonary vascular remodeling initiates these processes is very important. We used a well-characterized monocrotaline (MCT)-induced rat...
Autores principales: | Kiss, Tamas, Kovacs, Krisztina, Komocsi, Andras, Tornyos, Adrienn, Zalan, Petra, Sumegi, Balazs, Gallyas, Ferenc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136836/ https://www.ncbi.nlm.nih.gov/pubmed/25133539 http://dx.doi.org/10.1371/journal.pone.0104890 |
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