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A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A
Kinetochores are megadalton-sized protein complexes that mediate chromosome–microtubule interactions in eukaryotes. How kinetochore assembly is triggered specifically on centromeric chromatin is poorly understood. Here we use biochemical reconstitution experiments alongside genetic and structural an...
Autores principales: | Hornung, Peter, Troc, Paulina, Malvezzi, Francesca, Maier, Michael, Demianova, Zuzana, Zimniak, Tomasz, Litos, Gabriele, Lampert, Fabienne, Schleiffer, Alexander, Brunner, Matthias, Mechtler, Karl, Herzog, Franz, Marlovits, Thomas C., Westermann, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137059/ https://www.ncbi.nlm.nih.gov/pubmed/25135934 http://dx.doi.org/10.1083/jcb.201403081 |
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