High density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor

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Guanylyl cyclases (GCs), which synthesize the messenger cyclic guanosine 3′,5′-monophosphate, control several sensory functions, such as phototransduction, chemosensation, and thermosensation, in many species from worms to mammals. The GC chemoreceptor in sea urchin sperm can decode chemoattractant...

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Detalles Bibliográficos
Autores principales: Pichlo, Magdalena, Bungert-Plümke, Stefanie, Weyand, Ingo, Seifert, Reinhard, Bönigk, Wolfgang, Strünker, Timo, Kashikar, Nachiket Dilip, Goodwin, Normann, Müller, Astrid, Körschen, Heinz G., Collienne, Ursel, Pelzer, Patric, Van, Qui, Enderlein, Jörg, Klemm, Clementine, Krause, Eberhard, Trötschel, Christian, Poetsch, Ansgar, Kremmer, Elisabeth, Kaupp, U. Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137060/
https://www.ncbi.nlm.nih.gov/pubmed/25135936
http://dx.doi.org/10.1083/jcb.201402027
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