OX26/CTX-conjugated PEGylated liposome as a dual-targeting gene delivery system for brain glioma

BACKGROUND: The successful gene delivery into the brain is a major challenge due to the presence of the blood–brain barrier (BBB). In order to transport plasmid DNA across the BBB and target the brain glioma, the PEGylated liposomes (PLs) modified with OX26 and chlorotoxin (CTX) were developed as a...

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Detalles Bibliográficos
Autores principales: Yue, Pei-jian, He, Lei, Qiu, Shu-wei, Li, Yi, Liao, Yi-ji, Li, Xiang-pen, Xie, Dan, Peng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137094/
https://www.ncbi.nlm.nih.gov/pubmed/25128329
http://dx.doi.org/10.1186/1476-4598-13-191

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