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Chemical glycosylation of cytochrome c improves physical and chemical protein stability

BACKGROUND: Cytochrome c (Cyt c) is an apoptosis-initiating protein when released into the cytoplasm of eukaryotic cells and therefore a possible cancer drug candidate. Although proteins have been increasingly important as pharmaceutical agents, their chemical and physical instability during product...

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Detalles Bibliográficos
Autores principales: Delgado, Yamixa, Morales-Cruz, Moraima, Hernández-Román, José, Martínez, Yashira, Griebenow, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137108/
https://www.ncbi.nlm.nih.gov/pubmed/25095792
http://dx.doi.org/10.1186/1471-2091-15-16

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