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Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation

The goal of the current work was to profile positive (mTORC1 activation, autocrine/paracrine growth factors) and negative [AMPK, unfolded protein response (UPR)] pathways that might regulate overload-induced mTORC1 (mTOR complex 1) activation with the hypothesis that a number of negative regulators...

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Detalles Bibliográficos
Autores principales:	Lee Hamilton, D., Philp, Andrew, MacKenzie, Matthew G., Patton, Amy, Towler, Mhairi C., Gallagher, Iain J., Bodine, Sue C., Baar, Keith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137116/ https://www.ncbi.nlm.nih.gov/pubmed/24961241 http://dx.doi.org/10.1152/ajpendo.00674.2013

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