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An optimal ubiquitin-proteasome pathway in the nervous system: the role of deubiquitinating enzymes

The Ubiquitin-Proteasome Pathway (UPP), which is critical for normal function in the nervous system and is implicated in various neurological diseases, requires the small modifier protein ubiquitin to accomplish its duty of selectively degrading short-lived, abnormal or misfolded proteins. Over the...

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Detalles Bibliográficos
Autores principales: Ristic, Gorica, Tsou, Wei-Ling, Todi, Sokol V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137239/
https://www.ncbi.nlm.nih.gov/pubmed/25191222
http://dx.doi.org/10.3389/fnmol.2014.00072