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The Effect of Alcohol Intoxication on Mortality of Blunt Head Injury

Alcohol is found to have neuroprotection in recent studies in head injuries. We investigated the association of blood alcohol concentration (BAC) with mortality of patients with blunt head injury after traffic accident. All patients sustaining blunt head injury caused by traffic accident brought to...

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Autores principales: Lin, Hsing-Lin, Lin, Tsung-Ying, Soo, Kwan-Ming, Chen, Chao-Wen, Kuo, Liang-Chi, Lin, Yen-Ko, Lee, Wei-Che, Lin, Chih-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137490/
https://www.ncbi.nlm.nih.gov/pubmed/25157364
http://dx.doi.org/10.1155/2014/619231
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author Lin, Hsing-Lin
Lin, Tsung-Ying
Soo, Kwan-Ming
Chen, Chao-Wen
Kuo, Liang-Chi
Lin, Yen-Ko
Lee, Wei-Che
Lin, Chih-Lung
author_facet Lin, Hsing-Lin
Lin, Tsung-Ying
Soo, Kwan-Ming
Chen, Chao-Wen
Kuo, Liang-Chi
Lin, Yen-Ko
Lee, Wei-Che
Lin, Chih-Lung
author_sort Lin, Hsing-Lin
collection PubMed
description Alcohol is found to have neuroprotection in recent studies in head injuries. We investigated the association of blood alcohol concentration (BAC) with mortality of patients with blunt head injury after traffic accident. All patients sustaining blunt head injury caused by traffic accident brought to our emergency department who had obtained a brain computed tomography scans and BAC were analyzed. Patients with unknown mechanisms, transfers from outside hospitals, and incomplete data were excluded. Logistic regression was used to identify independent predictors of mortality. During the study period, 3,628 patients with brain computed tomography (CT) were included. Of these, BAC was measured in 556 patients. Patients with the lowest BAC (less than 8 mg/dl) had lower mortality; intoxicated patients with BAC between 8 and less than 100 mg/dl were associated with significantly higher mortality than those patients in other intoxicated groups. Adjusted logistic regression demonstrated higher BAC group and Glasgow coma scale (GCS) scores, and lower ISS and age were identified as independent predictors of reduced mortality. In our study, we found that patients who had moderate alcohol intoxication had higher risk of mortality. However, higher GCS scores, lower ISS, and younger age were identified as independent predictors of reduced mortality in the study patients.
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spelling pubmed-41374902014-08-25 The Effect of Alcohol Intoxication on Mortality of Blunt Head Injury Lin, Hsing-Lin Lin, Tsung-Ying Soo, Kwan-Ming Chen, Chao-Wen Kuo, Liang-Chi Lin, Yen-Ko Lee, Wei-Che Lin, Chih-Lung Biomed Res Int Research Article Alcohol is found to have neuroprotection in recent studies in head injuries. We investigated the association of blood alcohol concentration (BAC) with mortality of patients with blunt head injury after traffic accident. All patients sustaining blunt head injury caused by traffic accident brought to our emergency department who had obtained a brain computed tomography scans and BAC were analyzed. Patients with unknown mechanisms, transfers from outside hospitals, and incomplete data were excluded. Logistic regression was used to identify independent predictors of mortality. During the study period, 3,628 patients with brain computed tomography (CT) were included. Of these, BAC was measured in 556 patients. Patients with the lowest BAC (less than 8 mg/dl) had lower mortality; intoxicated patients with BAC between 8 and less than 100 mg/dl were associated with significantly higher mortality than those patients in other intoxicated groups. Adjusted logistic regression demonstrated higher BAC group and Glasgow coma scale (GCS) scores, and lower ISS and age were identified as independent predictors of reduced mortality. In our study, we found that patients who had moderate alcohol intoxication had higher risk of mortality. However, higher GCS scores, lower ISS, and younger age were identified as independent predictors of reduced mortality in the study patients. Hindawi Publishing Corporation 2014 2014-08-04 /pmc/articles/PMC4137490/ /pubmed/25157364 http://dx.doi.org/10.1155/2014/619231 Text en Copyright © 2014 Hsing-Lin Lin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Lin, Hsing-Lin
Lin, Tsung-Ying
Soo, Kwan-Ming
Chen, Chao-Wen
Kuo, Liang-Chi
Lin, Yen-Ko
Lee, Wei-Che
Lin, Chih-Lung
The Effect of Alcohol Intoxication on Mortality of Blunt Head Injury
title The Effect of Alcohol Intoxication on Mortality of Blunt Head Injury
title_full The Effect of Alcohol Intoxication on Mortality of Blunt Head Injury
title_fullStr The Effect of Alcohol Intoxication on Mortality of Blunt Head Injury
title_full_unstemmed The Effect of Alcohol Intoxication on Mortality of Blunt Head Injury
title_short The Effect of Alcohol Intoxication on Mortality of Blunt Head Injury
title_sort effect of alcohol intoxication on mortality of blunt head injury
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137490/
https://www.ncbi.nlm.nih.gov/pubmed/25157364
http://dx.doi.org/10.1155/2014/619231
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