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PARP1-Driven Apoptosis in Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia (CLL) is considered a malignancy resulting from defects in apoptosis. For this reason, targeting apoptotic pathways in CLL may be valuable for its management. Poly [ADP-ribose] polymerase 1 (PARP1) is the main member of a family of nuclear enzymes that act as DNA damage...
Autores principales: | Diamantopoulos, Panagiotis T., Sofotasiou, Maria, Papadopoulou, Vasiliki, Polonyfi, Katerina, Iliakis, Theodoros, Viniou, Nora-Athina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137605/ https://www.ncbi.nlm.nih.gov/pubmed/25161998 http://dx.doi.org/10.1155/2014/106713 |
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