Multi-parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes

The appearance of circulating islet-specific autoantibodies before disease diagnosis is a hallmark of human type 1 diabetes (T1D), and suggests a role for B cells in the pathogenesis of the disease. Alterations in the peripheral B cell compartment have been reported in T1D patients; however, to date...

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Detalles Bibliográficos
Autores principales: Thompson, W S, Pekalski, M L, Simons, H Z, Smyth, D J, Castro-Dopico, X, Guo, H, Guy, C, Dunger, D B, Arif, S, Peakman, M, Wallace, C, Wicker, L S, Todd, J A, Ferreira, R C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137841/
https://www.ncbi.nlm.nih.gov/pubmed/24773525
http://dx.doi.org/10.1111/cei.12362

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