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The Cytoplasmic Capping Complex Assembles on Adapter Protein Nck1 Bound to the Proline-Rich C-Terminus of Mammalian Capping Enzyme

Cytoplasmic capping is catalyzed by a complex that contains capping enzyme (CE) and a kinase that converts RNA with a 5′-monophosphate end to a 5′ diphosphate for subsequent addition of guanylic acid (GMP). We identify the proline-rich C-terminus as a new domain of CE that is required for its partic...

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Detalles Bibliográficos
Autores principales: Mukherjee, Chandrama, Bakthavachalu, Baskar, Schoenberg, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138027/
https://www.ncbi.nlm.nih.gov/pubmed/25137142
http://dx.doi.org/10.1371/journal.pbio.1001933