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Assessment of EGFR Mutations in Circulating Tumor Cell Preparations from NSCLC Patients by Next Generation Sequencing: Toward a Real-Time Liquid Biopsy for Treatment

INTRODUCTION: Assessment of EGFR mutation in non-small cell lung cancer (NSCLC) patients is mandatory for optimization of pharmacologic treatment. In this respect, mutation analysis of circulating tumor cells (CTCs) may be desirable since they may provide real-time information on patient's dise...

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Detalles Bibliográficos
Autores principales: Marchetti, Antonio, Del Grammastro, Maela, Felicioni, Lara, Malatesta, Sara, Filice, Giampaolo, Centi, Irene, De Pas, Tommaso, Santoro, Armando, Chella, Antonio, Brandes, Alba Ariela, Venturino, Paola, Cuccurullo, Franco, Crinò, Lucio, Buttitta, Fiamma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138040/
https://www.ncbi.nlm.nih.gov/pubmed/25137181
http://dx.doi.org/10.1371/journal.pone.0103883