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Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis

[Image: see text] The X-ray crystal structure of arginase from Schistosoma mansoni (SmARG) and the structures of its complexes with several amino acid inhibitors have been determined at atomic resolution. SmARG is a binuclear manganese metalloenzyme that catalyzes the hydrolysis of l-arginine to for...

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Detalles Bibliográficos
Autores principales:	Hai, Yang, Edwards, Jennifer E., Van Zandt, Michael C., Hoffmann, Karl F., Christianson, David W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138072/ https://www.ncbi.nlm.nih.gov/pubmed/25007099 http://dx.doi.org/10.1021/bi5004519

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