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Chemically Modified Peptide Scaffolds Target the CFTR-Associated Ligand PDZ Domain

PDZ domains are protein-protein interaction modules that coordinate multiple signaling and trafficking pathways in the cell and that include active therapeutic targets for diseases such as cancer, cystic fibrosis, and addiction. Our previous work characterized a PDZ interaction that restricts the ap...

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Detalles Bibliográficos
Autores principales:	Amacher, Jeanine F., Zhao, Ruizhi, Spaller, Mark R., Madden, Dean R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138078/ https://www.ncbi.nlm.nih.gov/pubmed/25136860 http://dx.doi.org/10.1371/journal.pone.0103650

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