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The Ginsenoside 20-O-β-D-Glucopyranosyl-20(S)-Protopanaxadiol Induces Autophagy and Apoptosis in Human Melanoma via AMPK/JNK Phosphorylation
Studies have shown that a major metabolite of the red ginseng ginsenoside Rb1, called 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (GPD), exhibits anticancer properties. However, the chemotherapeutic effects and molecular mechanisms behind GPD action in human melanoma have not been previously inves...
Autores principales: | Kang, Soouk, Kim, Jong-Eun, Song, Nu Ry, Jung, Sung Keun, Lee, Mee Hyun, Park, Jun Seong, Yeom, Myeong-Hun, Bode, Ann M., Dong, Zigang, Lee, Ki Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138097/ https://www.ncbi.nlm.nih.gov/pubmed/25137374 http://dx.doi.org/10.1371/journal.pone.0104305 |
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