Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL), a New Method to Detect Translocations in Leukemia

Here we present a novel method “Genomic inverse PCR for exploration of ligated breakpoints” (GIPFEL) that allows the sensitive detection of recurrent chromosomal translocations. This technique utilizes limited amounts of DNA as starting material and relies on PCR based quantification of unique DNA s...

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Detalles Bibliográficos
Autores principales: Fueller, Elisa, Schaefer, Daniel, Fischer, Ute, Krell, Pina F. I., Stanulla, Martin, Borkhardt, Arndt, Slany, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138100/
https://www.ncbi.nlm.nih.gov/pubmed/25137060
http://dx.doi.org/10.1371/journal.pone.0104419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138100/
https://www.ncbi.nlm.nih.gov/pubmed/25137060
http://dx.doi.org/10.1371/journal.pone.0104419

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