Molecular Analysis of Aedes aegypti Classical Protein Tyrosine Phosphatases Uncovers an Ortholog of Mammalian PTP-1B Implicated in the Control of Egg Production in Mosquitoes

BACKGROUND: Protein Tyrosine Phosphatases (PTPs) are enzymes that catalyze phosphotyrosine dephosphorylation and modulate cell differentiation, growth and metabolism. In mammals, PTPs play a key role in the modulation of canonical pathways involved in metabolism and immunity. PTP1B is the prototype...

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Detalles Bibliográficos
Autores principales: Moretti, Debora Monteiro, Ahuja, Lalima Gagan, Nunes, Rodrigo Dutra, Cudischevitch, Cecília Oliveira, Daumas-Filho, Carlos Renato Oliveira, Medeiros-Castro, Priscilla, Ventura-Martins, Guilherme, Jablonka, Willy, Gazos-Lopes, Felipe, Senna, Raquel, Sorgine, Marcos Henrique Ferreira, Hartfelder, Klaus, Capurro, Margareth, Atella, Georgia Correa, Mesquita, Rafael Dias, Silva-Neto, Mário Alberto Cardoso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138107/
https://www.ncbi.nlm.nih.gov/pubmed/25137153
http://dx.doi.org/10.1371/journal.pone.0104878

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