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Ire1 Mediated mRNA Splicing in a C-Terminus Deletion Mutant of Drosophila Xbp1

The Unfolded Protein Response is a homeostatic mechanism that permits eukaryotic cells to cope with Endoplasmic Reticulum (ER) stress caused by excessive accumulation of misfolded proteins in the ER lumen. The more conserved branch of the UPR relies on an ER transmembrane enzyme, Ire1, which, upon E...

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Detalles Bibliográficos
Autores principales: Coelho, Dina S., Gaspar, Catarina J., Domingos, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138184/
https://www.ncbi.nlm.nih.gov/pubmed/25136861
http://dx.doi.org/10.1371/journal.pone.0105588