Cargando…

Ire1 Mediated mRNA Splicing in a C-Terminus Deletion Mutant of Drosophila Xbp1

The Unfolded Protein Response is a homeostatic mechanism that permits eukaryotic cells to cope with Endoplasmic Reticulum (ER) stress caused by excessive accumulation of misfolded proteins in the ER lumen. The more conserved branch of the UPR relies on an ER transmembrane enzyme, Ire1, which, upon E...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coelho, Dina S., Gaspar, Catarina J., Domingos, Pedro M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138184/ https://www.ncbi.nlm.nih.gov/pubmed/25136861 http://dx.doi.org/10.1371/journal.pone.0105588

Ejemplares similares

Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay
por: Cairrão, Fátima, et al.
Publicado: (2022)

Ebola Virus Activates IRE1α-Dependent XBP1u Splicing
por: Rohde, Cornelius, et al.
Publicado: (2022)

Ire1 Has Distinct Catalytic Mechanisms for XBP1/HAC1 Splicing and RIDD
por: Tam, Arvin B., et al.
Publicado: (2014)

The requirement of IRE1 and XBP1 in resolving physiological stress during Drosophila development
por: Huang, Huai-Wei, et al.
Publicado: (2017)

Physiological roles of regulated Ire1 dependent decay
por: Coelho, Dina S., et al.
Publicado: (2014)

Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish
por: Ishikawa, Tokiro, et al.
Publicado: (2017)

Targeting XBP1 mRNA splicing sensitizes glioblastoma to chemotherapy
por: Dowdell, Amiee, et al.
Publicado: (2023)

Inhibition of IRE1α-mediated XBP1 mRNA cleavage by XBP1 reveals a novel regulatory process during the unfolded protein response
por: Chalmers, Fiona, et al.
Publicado: (2017)

IRE1α protects against osteoarthritis by regulating progranulin-dependent XBP1 splicing and collagen homeostasis
por: Liang, Li, et al.
Publicado: (2023)

Reconstitution and characterization of the unconventional splicing of XBP1u mRNA in vitro
por: Shinya, Sayoko, et al.
Publicado: (2011)

Fat body Ire1 regulates lipid homeostasis through the Xbp1s-FoxO axis in Drosophila
por: Zhao, Peng, et al.
Publicado: (2021)

Triazoloacridone C-1305 impairs XBP1 splicing by acting as a potential IRE1α endoribonuclease inhibitor
por: Bartoszewska, Sylwia, et al.
Publicado: (2021)

Genome-wide mRNA profiling identifies X-box-binding protein 1 (XBP1) as an IRE1 and PUMA repressor
por: Gebert, Magdalena, et al.
Publicado: (2021)

Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress
por: Bright, Michael D., et al.
Publicado: (2015)

xbp-1 mRNA splicing is attenuated under prolonged exposure to ER stress
por: Tsialikas, Jennifer, et al.
Publicado: (2017)

Role of IRE1α/XBP-1 in Cystic Fibrosis Airway Inflammation
por: Ribeiro, Carla M. P., et al.
Publicado: (2017)

IRE1α Promotes Zika Virus Infection via XBP1
por: Kolpikova, Elena P., et al.
Publicado: (2020)

Endoplasmic reticulum stress enhances fibrosis through IRE1α‐mediated degradation of miR‐150 and XBP‐1 splicing
por: Heindryckx, Femke, et al.
Publicado: (2016)

Incorporation of the Endoplasmic Reticulum Stress-Induced Spliced Form of XBP1 mRNA in the Exosomes
por: Hosoi, Toru, et al.
Publicado: (2018)

Live imaging of the co-translational recruitment of XBP1 mRNA to the ER and its processing by diffuse, non-polarized IRE1α
por: Gómez-Puerta, Silvia, et al.
Publicado: (2022)

Pharmacologic IRE1/XBP1s Activation Confers Targeted ER Proteostasis Reprogramming
por: Grandjean, Julia M.D., et al.
Publicado: (2020)

The Role of BiP and the IRE1α–XBP1 Axis in Rhabdomyosarcoma Pathology
por: Aghaei, Mahmoud, et al.
Publicado: (2021)

Pharmacologic IRE1/XBP1s activation promotes systemic adaptive remodeling in obesity
por: Madhavan, Aparajita, et al.
Publicado: (2022)

Involvement of miR-190b in Xbp1 mRNA Splicing upon Tocotrienol Treatment
por: Ambra, Roberto, et al.
Publicado: (2020)

Deletion of the N-terminus of SF2/ASF Permits RS-Domain-Independent Pre-mRNA Splicing
por: Shaw, Stephanie D., et al.
Publicado: (2007)

The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells
por: Hassler, Justin R., et al.
Publicado: (2015)

Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response
por: Jiang, Dadi, et al.
Publicado: (2016)

IRE1–XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells
por: Tsuchiya, Yuichi, et al.
Publicado: (2018)

IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing’s sarcoma
por: Tanabe, Yu, et al.
Publicado: (2018)

Genomic targets of the IRE1-XBP1s pathway in mediating metabolic adaptation in epithelial plasticity
por: Qiao, Dianhua, et al.
Publicado: (2023)

The Role of IRE-XBP1 Pathway in Regulation of Retinal Pigment Epithelium Tight Junctions
por: Ma, Jacey H., et al.
Publicado: (2016)

Physiological IRE-1-XBP-1 and PEK-1 Signaling in Caenorhabditis elegans Larval Development and Immunity
por: Richardson, Claire E., et al.
Publicado: (2011)

Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer
por: Lin, Jianhuang, et al.
Publicado: (2021)

Acute Endoplasmic Reticulum Stress-Independent Unconventional Splicing of XBP1 mRNA in the Nucleus of Mammalian Cells
por: Wang, Yuanyuan, et al.
Publicado: (2015)

Unfolded protein response mediator, the IRE1α-XBP1 pathway is involved in osteoblast differentiation
por: Tohmonda, Takahide, et al.
Publicado: (2012)

IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling
por: Sheng, Xia, et al.
Publicado: (2019)

Correction: IRE1–XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells
por: Tsuchiya, Yuichi, et al.
Publicado: (2019)

IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity
por: Song, Minkyung, et al.
Publicado: (2018)

Mouse Hepatitis Virus Infection Activates the IRE1/XBP1 Pathway of the Unfolded Protein Response
por: Bechill, John, et al.
Publicado: (2006)

Bip-Yorkie interaction determines oncogenic and tumor-suppressive roles of Ire1/Xbp1s activation
por: Yang, Shuai, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4pt8emrledvlqco73bkvfss0j0