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The IκB Kinase Complex Is Required for Plexin-B-Mediated Activation of RhoA
Plexins are widely expressed transmembrane proteins that mediate the cellular effects of semaphorins. The molecular mechanisms of plexin-mediated signal transduction are still poorly understood. Here we show that signalling via B-family plexins leading to the activation of the small GTPase RhoA requ...
Autores principales: | Zielonka, Matthias, Krishnan, Ramesh K., Swiercz, Jakub M., Offermanns, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138210/ https://www.ncbi.nlm.nih.gov/pubmed/25137062 http://dx.doi.org/10.1371/journal.pone.0105661 |
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