Cargando…

The Complex Relationship Between Inflammation And Lung Function In Severe Asthma

Asthma is a common respiratory disease affecting approximately 300 million people worldwide. Airway inflammation is thought to contribute to asthma pathogenesis, but the direct relationship between inflammation and airway hyperresponsiveness remains unclear. This study investigates the role of infla...

Descripción completa

Detalles Bibliográficos
Autores principales:	Manni, Michelle L., Trudeau, John B., Scheller, Erich V., Mandalapu, Sivanarayana, Elloso, M. Merle, Kolls, Jay K., Wenzel, Sally E., Alcorn, John F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138304/ https://www.ncbi.nlm.nih.gov/pubmed/24549277 http://dx.doi.org/10.1038/mi.2014.8

Ejemplares similares

Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease
por: Manni, Michelle L., et al.
Publicado: (2017)

The role of IL-27 in susceptibility to post-influenza Staphylococcus aureus pneumonia
por: Robinson, Keven M, et al.
Publicado: (2015)

A Novel Outbred Mouse Model of 2009 Pandemic Influenza and Bacterial Co-Infection Severity
por: McHugh, Kevin J., et al.
Publicado: (2013)

Differential Requirement for c-Jun N-terminal Kinase 1 in Lung Inflammation and Host Defense
por: Van der Velden, Jos, et al.
Publicado: (2012)

123 Influenza-induced Susceptibility to Secondary Bacterial Pneumonia Is Rescued in STAT2-/- Mice Via an IL-23 Independent Mechanism
por: Lee, Benjamin, et al.
Publicado: (2014)

Vitamin D supplementation decreases Aspergillus fumigatus specific Th2 responses in CF patients with aspergillus sensitization: a phase one open-label study
por: Nguyen, Nikki Lynn Hue, et al.
Publicado: (2015)

Calprotectin-g the Lung during Type 2 Allergic Airway Inflammation
por: Manni, Michelle L., et al.
Publicado: (2019)

STAT2 Signaling Regulates Macrophage Phenotype During Influenza and Bacterial Super-Infection
por: Gopal, Radha, et al.
Publicado: (2018)

High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status
por: Camiolo, Matthew J., et al.
Publicado: (2021)

Insights Into Type I and III Interferons in Asthma and Exacerbations
por: Rich, Helen E., et al.
Publicado: (2020)

Precision medicine in pediatric severe asthma: Targeted blockade of type 2 inflammation
por: Larkin, Allyson S., et al.
Publicado: (2022)

Development of New Therapies for Severe Asthma
por: Fajt, Merritt L., et al.
Publicado: (2017)

Severe Adult Asthmas: Integrating Clinical Features, Biology, and Therapeutics to Improve Outcomes
por: Wenzel, Sally E.
Publicado: (2021)

Should lung biopsies be performed in patients with severe asthma?
por: Doberer, Daniel, et al.
Publicado: (2015)

975. Roles of Type I and III Interferon in Severe Pathogenesis of Human Metapneumovirus
por: Williams, John V, et al.
Publicado: (2019)

Commentary: Understanding the Impact of Infection, Inflammation and Their Persistence in the Pathogenesis of Bronchopulmonary Dysplasia
por: Kolls, Jay K.
Publicado: (2017)

Airway Microbiota in Severe Asthma and Relationship to Asthma Severity and Phenotypes
por: Zhang, Qingling, et al.
Publicado: (2016)

IL-22 Binding Protein Exacerbates Influenza, Bacterial Super-infection
por: Abood, Robert N., et al.
Publicado: (2019)

Obesity, Inflammation, and Severe Asthma: an Update
por: Sharma, Varun, et al.
Publicado: (2021)

Relationship between Vitamin D, Inflammation and Lung Function In Patients with Severe Uncontrolled Asthma
por: Janeva-Jovanovska, Elena, et al.
Publicado: (2017)

An observational study to determine the relationship between cough frequency and markers of inflammation in severe asthma
por: Holmes, Joshua, et al.
Publicado: (2022)

The relationship between the Leicester cough questionnaire, eosinophilic airway inflammation and asthma patient related outcomes in severe adult asthma
por: Natarajan, Sushiladevi, et al.
Publicado: (2017)

Asthma
por: Holgate, Stephen T., et al.
Publicado: (2015)

Machine learning implicates the IL-18 signaling axis in severe asthma
por: Camiolo, Matthew J., et al.
Publicado: (2021)

Poster 1023: Dupilumab suppresses Th2 inflammation in adult asthma and atopic dermatitis
por: Swanson, Brian, et al.
Publicado: (2014)

The relationship of asthma severity to COVID-19 outcomes
por: Zein, Joe G., et al.
Publicado: (2022)

Conserved natural IgM antibodies mediate innate and adaptive immunity against the opportunistic fungus Pneumocystis murina
por: Rapaka, Rekha R., et al.
Publicado: (2010)

Asthma Is More Severe in Older Adults
por: Zein, Joe G., et al.
Publicado: (2015)

Relationship of Pneumocystis antibody responses to paediatric asthma severity
por: Rayens, Emily, et al.
Publicado: (2021)

Differential Regulation of Inflammation and Immunity in Mild and Severe Experimental Asthma
por: Sagar, Seil, et al.
Publicado: (2013)

Implication of IL-18 in chronic inflammation of severe refractory asthma
por: Rovina, Nikoletta, et al.
Publicado: (2015)

NETopathic Inflammation in Chronic Obstructive Pulmonary Disease and Severe Asthma
por: Uddin, Mohib, et al.
Publicado: (2019)

Measuring inflammation in paediatric severe asthma: biomarkers in clinical practice
por: Licari, Amelia, et al.
Publicado: (2020)

Eosinophilic inflammation: An Appealing Target for Pharmacologic Treatments in Severe Asthma
por: Vatrella, Alessandro, et al.
Publicado: (2022)

Airway Inflammation Before and After Bronchial Thermoplasty in Severe Asthma
por: Wijsman, Pieta C, et al.
Publicado: (2022)

Bronchiectasis in severe asthma is associated with eosinophilic airway inflammation and activation
por: Frøssing, Laurits, et al.
Publicado: (2022)

Immune Modulatory Effects of IL-22 on Allergen-Induced Pulmonary Inflammation
por: Fang, Ping, et al.
Publicado: (2014)

An Airway Epithelial iNOS-DUOX2-Thyroid Peroxidase Metabolome Drives Th1/Th2 Nitrative Stress in Human Severe Asthma
por: Voraphani, N, et al.
Publicado: (2014)

Determining asthma endotypes and outcomes: Complementing existing clinical practice with modern machine learning
por: Ray, Anuradha, et al.
Publicado: (2022)

Is it severe asthma or asthma with severe comorbidities?
por: Brussino, Luisa, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jbqid8cu1dv7l2s16rofuivcdh