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A modified dinucleotide motif specifies tRNA recognition by TLR7

RNA can function as a pathogen-associated molecular pattern (PAMP) whose recognition by the innate immune system alerts the body to an impending microbial infection. The recognition of tRNA as either self or nonself RNA by TLR7 depends on its modification patterns. In particular, it is known that th...

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Detalles Bibliográficos
Autores principales:	Kaiser, Steffen, Rimbach, Katharina, Eigenbrod, Tatjana, Dalpke, Alexander H., Helm, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2014
Materias:	Letter to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138318/ https://www.ncbi.nlm.nih.gov/pubmed/25051971 http://dx.doi.org/10.1261/rna.044024.113

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