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The role of RNA structure at 5′ untranslated region in microRNA-mediated gene regulation

Recent studies have suggested that the secondary structure of the 5′ untranslated region (5′ UTR) of messenger RNA (mRNA) is important for microRNA (miRNA)-mediated gene regulation in humans. mRNAs that are targeted by miRNA tend to have a higher degree of local secondary structure in their 5′ UTR;...

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Detalles Bibliográficos
Autores principales: Gu, Wanjun, Xu, Yuming, Xie, Xueying, Wang, Ting, Ko, Jae-Hong, Zhou, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138320/
https://www.ncbi.nlm.nih.gov/pubmed/25002673
http://dx.doi.org/10.1261/rna.044792.114

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