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Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1

MicroRNAs (miRNAs) play critical roles in a variety of biological processes through widespread effects on protein synthesis. Upon association with the miRNA-induced silencing complex (miRISC), miRNAs repress target mRNA translation and accelerate mRNA decay. Degradation of the mRNA is initiated by s...

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Detalles Bibliográficos
Autores principales:	Rouya, Christopher, Siddiqui, Nadeem, Morita, Masahiro, Duchaine, Thomas F., Fabian, Marc R., Sonenberg, Nahum
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138323/ https://www.ncbi.nlm.nih.gov/pubmed/25035296 http://dx.doi.org/10.1261/rna.045302.114

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