Superior antigen-specific CD4(+)T-cell response with AS03-adjuvantation of a trivalent influenza vaccine in a randomised trial of adults aged 65 and older

BACKGROUND: The effectiveness of trivalent influenza vaccines may be reduced in older versus younger adults because of age-related immunosenescence. The use of an adjuvant in such a vaccine is one strategy that may combat immunosenescence, potentially by bolstering T-cell mediated responses. METHODS...

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Detalles Bibliográficos
Autores principales: Couch, Robert B, Bayas, José M, Caso, Covadonga, Mbawuike, Innocent Nnadi, López, Concepción Núñez, Claeys, Carine, El Idrissi, Mohamed, Hervé, Caroline, Laupèze, Béatrice, Oostvogels, Lidia, Moris, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138369/
https://www.ncbi.nlm.nih.gov/pubmed/25078387
http://dx.doi.org/10.1186/1471-2334-14-425

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