Cargando…
Impact of dairy consumption on essential hypertension: a clinical study
BACKGROUND: Several studies have presented evidence suggesting that dairy consumption has beneficial effects on blood pressure (BP) in healthy subjects; however, only a few studies have examined this possibility in patients with established essential hypertension using ambulatory blood pressure moni...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138376/ https://www.ncbi.nlm.nih.gov/pubmed/25123170 http://dx.doi.org/10.1186/1475-2891-13-83 |
_version_ | 1782331224584355840 |
---|---|
author | Drouin-Chartier, Jean-Philippe Gigleux, Iris Tremblay, André J Poirier, Luc Lamarche, Benoît Couture, Patrick |
author_facet | Drouin-Chartier, Jean-Philippe Gigleux, Iris Tremblay, André J Poirier, Luc Lamarche, Benoît Couture, Patrick |
author_sort | Drouin-Chartier, Jean-Philippe |
collection | PubMed |
description | BACKGROUND: Several studies have presented evidence suggesting that dairy consumption has beneficial effects on blood pressure (BP) in healthy subjects; however, only a few studies have examined this possibility in patients with established essential hypertension using ambulatory blood pressure monitoring. The objective of this study was to investigate how consuming dairy products impacts mean daytime systolic and diastolic BP in men and women with mild to moderate essential hypertension. METHODS: Eighty-nine men and women with systolic BP ≥ 135 mm Hg and ≤ 160 mm Hg and diastolic BP ≤ 110 mm Hg were enrolled in this single-blind, randomized, cross-over, controlled study. Participants had to incorporate three daily servings of dairy products or control products equivalent in macronutrients and sodium during four-week treatment phases. Twenty-four hour ambulatory BP and endothelial function were assessed at screening and at the end of each dietary phase. RESULTS: The consumption of three daily servings of dairy products led to a significant reduction in mean daytime ambulatory systolic BP (-2 mm Hg; P = 0.05) in men compared with readings after the control phase. In women, dairy consumption had no effect on ambulatory systolic BP. Moreover, endothelial function was significantly improved by dairy consumption in the whole cohort. CONCLUSION: These data indicate that the consumption of three daily servings of dairy products have beneficial effects on daytime systolic ambulatory BP compared to a heart-healthy, dairy-free, diet in men with mild to moderate essential hypertension. TRIAL REGISTRATION: This trial is registered at clinicaltrials.gov as NCT01776216. |
format | Online Article Text |
id | pubmed-4138376 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-41383762014-08-21 Impact of dairy consumption on essential hypertension: a clinical study Drouin-Chartier, Jean-Philippe Gigleux, Iris Tremblay, André J Poirier, Luc Lamarche, Benoît Couture, Patrick Nutr J Research BACKGROUND: Several studies have presented evidence suggesting that dairy consumption has beneficial effects on blood pressure (BP) in healthy subjects; however, only a few studies have examined this possibility in patients with established essential hypertension using ambulatory blood pressure monitoring. The objective of this study was to investigate how consuming dairy products impacts mean daytime systolic and diastolic BP in men and women with mild to moderate essential hypertension. METHODS: Eighty-nine men and women with systolic BP ≥ 135 mm Hg and ≤ 160 mm Hg and diastolic BP ≤ 110 mm Hg were enrolled in this single-blind, randomized, cross-over, controlled study. Participants had to incorporate three daily servings of dairy products or control products equivalent in macronutrients and sodium during four-week treatment phases. Twenty-four hour ambulatory BP and endothelial function were assessed at screening and at the end of each dietary phase. RESULTS: The consumption of three daily servings of dairy products led to a significant reduction in mean daytime ambulatory systolic BP (-2 mm Hg; P = 0.05) in men compared with readings after the control phase. In women, dairy consumption had no effect on ambulatory systolic BP. Moreover, endothelial function was significantly improved by dairy consumption in the whole cohort. CONCLUSION: These data indicate that the consumption of three daily servings of dairy products have beneficial effects on daytime systolic ambulatory BP compared to a heart-healthy, dairy-free, diet in men with mild to moderate essential hypertension. TRIAL REGISTRATION: This trial is registered at clinicaltrials.gov as NCT01776216. BioMed Central 2014-08-14 /pmc/articles/PMC4138376/ /pubmed/25123170 http://dx.doi.org/10.1186/1475-2891-13-83 Text en © Drouin-Chartier et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Drouin-Chartier, Jean-Philippe Gigleux, Iris Tremblay, André J Poirier, Luc Lamarche, Benoît Couture, Patrick Impact of dairy consumption on essential hypertension: a clinical study |
title | Impact of dairy consumption on essential hypertension: a clinical study |
title_full | Impact of dairy consumption on essential hypertension: a clinical study |
title_fullStr | Impact of dairy consumption on essential hypertension: a clinical study |
title_full_unstemmed | Impact of dairy consumption on essential hypertension: a clinical study |
title_short | Impact of dairy consumption on essential hypertension: a clinical study |
title_sort | impact of dairy consumption on essential hypertension: a clinical study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138376/ https://www.ncbi.nlm.nih.gov/pubmed/25123170 http://dx.doi.org/10.1186/1475-2891-13-83 |
work_keys_str_mv | AT drouinchartierjeanphilippe impactofdairyconsumptiononessentialhypertensionaclinicalstudy AT gigleuxiris impactofdairyconsumptiononessentialhypertensionaclinicalstudy AT tremblayandrej impactofdairyconsumptiononessentialhypertensionaclinicalstudy AT poirierluc impactofdairyconsumptiononessentialhypertensionaclinicalstudy AT lamarchebenoit impactofdairyconsumptiononessentialhypertensionaclinicalstudy AT couturepatrick impactofdairyconsumptiononessentialhypertensionaclinicalstudy |