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Regulation of HPV16 E6 and MCL1 by SF3B1 inhibitor in head and neck cancer cells

ABT-737 inhibits the anti-apoptotic proteins B-cell lymphoma 2 (BCL-2) and BCL-X(L). Meayamycin B switches the splicing pattern of myeloid cell leukemia factor 1 (MCL1) pre-mRNA. Specifically, inhibition of splicing factor 3B subunit 1 (SF3B1) with meayamycin B promotes the generation of the proapop...

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Detalles Bibliográficos
Autores principales:	Gao, Yang, Trivedi, Sumita, Ferris, Robert L., Koide, Kazunori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138523/ https://www.ncbi.nlm.nih.gov/pubmed/25139387 http://dx.doi.org/10.1038/srep06098

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