Mitochondrial ROS potentiates indirect activation of the AIM2 inflammasome

Activation of the inflammasome is important for the detection and clearance of cytosolic pathogens. In contrast to avirulent Francisella novicida (Fn), infection with virulent Francisella tularensis ssp tularensis does not trigger activation of the host AIM2 inflammasome. Here we show that different...

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Detalles Bibliográficos
Autores principales: Crane, Deborah D., Bauler, Timothy J., Wehrly, Tara D., Bosio, Catharine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138581/
https://www.ncbi.nlm.nih.gov/pubmed/25191316
http://dx.doi.org/10.3389/fmicb.2014.00438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138581/
https://www.ncbi.nlm.nih.gov/pubmed/25191316
http://dx.doi.org/10.3389/fmicb.2014.00438

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