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Efficacy of insulin lispro in improving glycemic control in gestational diabetes
AIM: To assess the safety and efficacy of insulin lispro in improving glycemic control in patients with gestational diabetes. MATERIALS AND METHODS: A retrospective observational study was conducted at a single center on 201 gestational women with diabetes. Subjects who received insulin lispro perfo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138903/ https://www.ncbi.nlm.nih.gov/pubmed/25143904 http://dx.doi.org/10.4103/2230-8210.137492 |
Sumario: | AIM: To assess the safety and efficacy of insulin lispro in improving glycemic control in patients with gestational diabetes. MATERIALS AND METHODS: A retrospective observational study was conducted at a single center on 201 gestational women with diabetes. Subjects who received insulin lispro performed blood glucose self-monitoring and recorded the readings in the fasting state and 1 h after each meal. At each contact (in person or telephonic contact), the insulin dose was adjusted based on the readings measured. A total of 53 subjects also recorded glucose levels post-partum. Pregnancy and post-delivery glucose level and insulin requirements of these 53 patients were compared. RESULTS: Analysis of glucose levels both fasting and post-prandial glucose levels revealed that after using insulin lispro, the number of episodes of post-prandial hyperglycemia (1 h plasma glucose >120 mg/dL) was minimal and so was the incidence of hypoglycemia. Hypoglycemia was defined as a blood sugar value of. There was neither any congenital abnormality except for a poorly formed pinna in the right ear of one baby nor any post-partum complications of note. CONCLUSION: Insulin lispro is an effective and safe treatment option in gestational diabetes. |
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