CLEC‐2‐dependent activation of mouse platelets is weakly inhibited by cAMP but not by cGMP

BACKGROUND: The activation of platelet CLEC‐2 by podoplanin on lymphatic endothelial cells (LECs) has a critical role in prevention of mixing of lymphatic and blood vasculatures during embryonic development. Paradoxically, LECs release cAMP and cGMP‐elevating agents, prostacyclin (PGI(2)) and nitric...

Descripción completa

Detalles Bibliográficos
Autores principales: Borgognone, A., Navarro‐Núñez, L., Correia, J. N., Pollitt, A. Y., Thomas, S. G., Eble, J. A., Pulcinelli, F. M., Madhani, M., Watson, S. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Pub 2014
Materias:
PLATELETS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138994/
https://www.ncbi.nlm.nih.gov/pubmed/24460629
http://dx.doi.org/10.1111/jth.12514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138994/
https://www.ncbi.nlm.nih.gov/pubmed/24460629
http://dx.doi.org/10.1111/jth.12514

Ejemplares similares