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Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity

Obesity is associated with blunted β-adrenoreceptor (β-AR)-mediated lipolysis and lipid oxidation in adipose tissue, but the mechanisms linking nutrient overload to catecholamine resistance are poorly understood. We report that targeted disruption of TGF-β superfamily receptor ALK7 alleviates diet-i...

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Detalles Bibliográficos
Autores principales:	Guo, Tingqing, Marmol, Patricia, Moliner, Annalena, Björnholm, Marie, Zhang, Chao, Shokat, Kevan M, Ibanez, Carlos F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Human Biology and Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139062/ https://www.ncbi.nlm.nih.gov/pubmed/25161195 http://dx.doi.org/10.7554/eLife.03245

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