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Target Repression Induced by Endogenous microRNAs: Large Differences, Small Effects

MicroRNAs are small RNAs that regulate protein levels. It is commonly assumed that the expression level of a microRNA is directly correlated with its repressive activity – that is, highly expressed microRNAs will repress their target mRNAs more. Here we investigate the quantitative relationship betw...

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Detalles Bibliográficos
Autores principales: Kozomara, Ana, Hunt, Suzanne, Ninova, Maria, Griffiths-Jones, Sam, Ronshaugen, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139194/
https://www.ncbi.nlm.nih.gov/pubmed/25141277
http://dx.doi.org/10.1371/journal.pone.0104286