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Intranasal Delivery of Influenza rNP Adjuvanted with c-di-AMP Induces Strong Humoral and Cellular Immune Responses and Provides Protection against Virus Challenge

There is a critical need for new influenza vaccines able to protect against constantly emerging divergent virus strains. This will be sustained by the induction of vigorous cellular responses and humoral immunity capable of acting at the portal of entry of this pathogen. In this study we evaluate th...

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Detalles Bibliográficos
Autores principales:	Sanchez, Maria Victoria, Ebensen, Thomas, Schulze, Kai, Cargnelutti, Diego, Blazejewska, Paulina, Scodeller, Eduardo A., Guzmán, Carlos A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139298/ https://www.ncbi.nlm.nih.gov/pubmed/25140692 http://dx.doi.org/10.1371/journal.pone.0104824

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