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Molecular Investigations of Protriptyline as a Multi-Target Directed Ligand in Alzheimer's Disease

Alzheimer's disease (AD) is a complex neurodegenerative disorder involving multiple cellular and molecular processes. The discovery of drug molecules capable of targeting multiple factors involved in AD pathogenesis would greatly facilitate in improving therapeutic strategies. The repositioning...

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Detalles Bibliográficos
Autores principales: Bansode, Sneha B., Jana, Asis K., Batkulwar, Kedar B., Warkad, Shrikant D., Joshi, Rakesh S., Sengupta, Neelanjana, Kulkarni, Mahesh J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139341/
https://www.ncbi.nlm.nih.gov/pubmed/25141174
http://dx.doi.org/10.1371/journal.pone.0105196