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Loss of estrogen-mediated immunoprotection underlies female gender bias in experimental Crohn’s-like ileitis

The incidence and severity of Crohn’s disease (CD) are increased in female patients. Using SAMP1/YitFc (SAMP) mice, a spontaneous model of chronic intestinal inflammation that displays histologic and pathogenic similarities to human CD, we investigated the potential mechanism(s) contributing to sex...

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Detalles Bibliográficos
Autores principales:	Goodman, Wendy A., Garg, Rekha R., Reuter, Brian K., Mattioli, Benedetta, Rissman, Emilie F., Pizarro, Theresa T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139459/ https://www.ncbi.nlm.nih.gov/pubmed/24621993 http://dx.doi.org/10.1038/mi.2014.15

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