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Intraoperative contrast-enhanced urosonography during endoscopic treatment of vesicoureteral reflux in children
BACKGROUND: There are many controversies surrounding the effectiveness of endoscopic treatment of vesicouretheral reflux (VUR) in children, thus it is of highest priority to analyze factors influencing the outcome of therapy and to search for new methods that would increase the success rate and redu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139583/ https://www.ncbi.nlm.nih.gov/pubmed/24718880 http://dx.doi.org/10.1007/s00247-014-2963-7 |
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author | Woźniak, Magdalena Maria Osemlak, Paweł Pawelec, Agata Brodzisz, Agnieszka Nachulewicz, Paweł Wieczorek, Andrzej Paweł Zajączkowska, Maria Małgorzata |
author_facet | Woźniak, Magdalena Maria Osemlak, Paweł Pawelec, Agata Brodzisz, Agnieszka Nachulewicz, Paweł Wieczorek, Andrzej Paweł Zajączkowska, Maria Małgorzata |
author_sort | Woźniak, Magdalena Maria |
collection | PubMed |
description | BACKGROUND: There are many controversies surrounding the effectiveness of endoscopic treatment of vesicouretheral reflux (VUR) in children, thus it is of highest priority to analyze factors influencing the outcome of therapy and to search for new methods that would increase the success rate and reduce the number of reinjections. OBJECTIVE: The aim of the study was to analyze whether intraoperative contrast-enhanced urosonography (ce-US) may increase the effectiveness of endoscopic anti-reflux therapy. MATERIALS AND METHODS: Intraoperative contrast-enhanced urosonography (ce-US) with SonoVue® was performed in 17 patients (25 ureteral units) undergoing endoscopic treatment of VUR. Ce-US was performed in the operating room before the procedure and after injection of the bulking material. When VUR persisted, the operator repeated the injection, which was followed by ce-US. The results were compared with those obtained from a control group (15 patients; 22 ureteral units). RESULTS: A repeat injection during a single endoscopic treatment was required in 24% of cases. The overall success rate confirmed at 6–12 months’ follow-ups was 84%. The success rate was significantly higher in comparison to the control group (success: 64%). CONCLUSION: Intraoperative ce-US performed during endoscopic treatment of VUR enables immediate monitoring of outcome and provides the opportunity for repeat injection during the same procedure, thus increasing the efficacy of the procedure and reducing the number of reinjections. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00247-014-2963-7) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4139583 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-41395832014-08-26 Intraoperative contrast-enhanced urosonography during endoscopic treatment of vesicoureteral reflux in children Woźniak, Magdalena Maria Osemlak, Paweł Pawelec, Agata Brodzisz, Agnieszka Nachulewicz, Paweł Wieczorek, Andrzej Paweł Zajączkowska, Maria Małgorzata Pediatr Radiol Original Article BACKGROUND: There are many controversies surrounding the effectiveness of endoscopic treatment of vesicouretheral reflux (VUR) in children, thus it is of highest priority to analyze factors influencing the outcome of therapy and to search for new methods that would increase the success rate and reduce the number of reinjections. OBJECTIVE: The aim of the study was to analyze whether intraoperative contrast-enhanced urosonography (ce-US) may increase the effectiveness of endoscopic anti-reflux therapy. MATERIALS AND METHODS: Intraoperative contrast-enhanced urosonography (ce-US) with SonoVue® was performed in 17 patients (25 ureteral units) undergoing endoscopic treatment of VUR. Ce-US was performed in the operating room before the procedure and after injection of the bulking material. When VUR persisted, the operator repeated the injection, which was followed by ce-US. The results were compared with those obtained from a control group (15 patients; 22 ureteral units). RESULTS: A repeat injection during a single endoscopic treatment was required in 24% of cases. The overall success rate confirmed at 6–12 months’ follow-ups was 84%. The success rate was significantly higher in comparison to the control group (success: 64%). CONCLUSION: Intraoperative ce-US performed during endoscopic treatment of VUR enables immediate monitoring of outcome and provides the opportunity for repeat injection during the same procedure, thus increasing the efficacy of the procedure and reducing the number of reinjections. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00247-014-2963-7) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2014-04-10 2014 /pmc/articles/PMC4139583/ /pubmed/24718880 http://dx.doi.org/10.1007/s00247-014-2963-7 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Original Article Woźniak, Magdalena Maria Osemlak, Paweł Pawelec, Agata Brodzisz, Agnieszka Nachulewicz, Paweł Wieczorek, Andrzej Paweł Zajączkowska, Maria Małgorzata Intraoperative contrast-enhanced urosonography during endoscopic treatment of vesicoureteral reflux in children |
title | Intraoperative contrast-enhanced urosonography during endoscopic treatment of vesicoureteral reflux in children |
title_full | Intraoperative contrast-enhanced urosonography during endoscopic treatment of vesicoureteral reflux in children |
title_fullStr | Intraoperative contrast-enhanced urosonography during endoscopic treatment of vesicoureteral reflux in children |
title_full_unstemmed | Intraoperative contrast-enhanced urosonography during endoscopic treatment of vesicoureteral reflux in children |
title_short | Intraoperative contrast-enhanced urosonography during endoscopic treatment of vesicoureteral reflux in children |
title_sort | intraoperative contrast-enhanced urosonography during endoscopic treatment of vesicoureteral reflux in children |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139583/ https://www.ncbi.nlm.nih.gov/pubmed/24718880 http://dx.doi.org/10.1007/s00247-014-2963-7 |
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