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DNA Break Mapping Reveals Topoisomerase II Activity Genome-Wide

Genomic DNA is under constant assault by endogenous and exogenous DNA damaging agents. DNA breakage can represent a major threat to genome integrity but can also be necessary for genome function. Here we present approaches to map DNA double-strand breaks (DSBs) and single-strand breaks (SSBs) at the...

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Detalles Bibliográficos
Autores principales:	Baranello, Laura, Kouzine, Fedor, Wojtowicz, Damian, Cui, Kairong, Przytycka, Teresa M., Zhao, Keji, Levens, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139894/ https://www.ncbi.nlm.nih.gov/pubmed/25056547 http://dx.doi.org/10.3390/ijms150713111

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