Cargando…

Multifunctional roles of the mammalian CCR4–NOT complex in physiological phenomena

The carbon catabolite repression 4 (CCR4)–negative on TATA-less (NOT) complex serves as one of the major deadenylases of eukaryotes. Although it was originally identified and characterized in yeast, recent studies have revealed that the CCR4–NOT complex also exerts important functions in mammals, -i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shirai, Yo-Taro, Suzuki, Toru, Morita, Masahiro, Takahashi, Akinori, Yamamoto, Tadashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139912/ https://www.ncbi.nlm.nih.gov/pubmed/25191340 http://dx.doi.org/10.3389/fgene.2014.00286

Ejemplares similares

The CCR4–NOT Deadenylase Complex Maintains Adipocyte Identity
por: Takahashi, Akinori, et al.
Publicado: (2019)

The CCR4–NOT deadenylase complex safeguards thymic positive selection by down-regulating aberrant pro-apoptotic gene expression
por: Ito-Kureha, Taku, et al.
Publicado: (2020)

Insights into the structure and architecture of the CCR4–NOT complex
por: Xu, Kun, et al.
Publicado: (2014)

The CCR4–NOT complex maintains liver homeostasis through mRNA deadenylation
por: Takahashi, Akinori, et al.
Publicado: (2020)

Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex
por: Winkler, G. Sebastiaan, et al.
Publicado: (2013)

Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability
por: Mostafa, Dina, et al.
Publicado: (2020)

Disruption of the Mammalian Ccr4–Not Complex Contributes to Transcription-Mediated Genome Instability
por: Hagkarim, Nafiseh Chalabi, et al.
Publicado: (2023)

Novel roles of the multi-functional CCR4-NOT complex in post-transcriptional regulation
por: Inada, Toshifumi, et al.
Publicado: (2014)

Deadenylation of mRNA by the CCR4–NOT complex in Drosophila: molecular and developmental aspects
por: Temme, Claudia, et al.
Publicado: (2014)

Regulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2
por: Suzuki, Toru, et al.
Publicado: (2022)

The cellular roles of Ccr4-NOT in model and pathogenic fungi—implications for fungal virulence
por: Panepinto, John C., et al.
Publicado: (2013)

Regulation of Early Lymphocyte Development via mRNA Decay Catalyzed by the CCR4-NOT Complex
por: Akiyama, Taishin, et al.
Publicado: (2021)

The CCR4–NOT complex suppresses untimely translational activation of maternal mRNAs
por: Soeda, Shou, et al.
Publicado: (2023)

The use of epigenetic phenomena for the improvement of sheep and cattle
por: Goddard, Michael E., et al.
Publicado: (2014)

Recent Positive Selection in Genes of the Mammalian Epidermal Differentiation Complex Locus
por: Goodwin, Zane A., et al.
Publicado: (2017)

Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes
por: Suzuki, Toru, et al.
Publicado: (2019)

A dual, catalytic role for the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading
por: Challal, Drice, et al.
Publicado: (2023)

Pleiotropy Complicates Human Gene Editing: CCR5Δ32 and Beyond
por: Li, Ting, et al.
Publicado: (2019)

Genetic diversity and prevalence of CCR2-CCR5 gene polymorphisms in the Omani population
por: Al-Mahruqi, Samira H., et al.
Publicado: (2014)

Specific recognition and ubiquitination of translating ribosomes by mammalian CCR4-NOT
por: Absmeier, Eva, et al.
Publicado: (2023)

Association of CCR5Δ32 Deletion and Human Cytomegalovirus Infection With Colorectal Cancer in Tunisia
por: Chelbi, Hanen, et al.
Publicado: (2021)

CCR5 as a Prognostic Factor in Lower-Grade Glioma is Involved in the Remodeling of the Tumor Microenvironment
por: Wang, Fang, et al.
Publicado: (2022)

Interaction between NANOS2 and the CCR4-NOT Deadenylation Complex Is Essential for Male Germ Cell Development in Mouse
por: Suzuki, Atsushi, et al.
Publicado: (2012)

Editorial: Epigenetics in Mammalian Tissues
por: Franco, Rafael, et al.
Publicado: (2019)

Radial Organization in the Mammalian Nucleus
por: Crosetto, Nicola, et al.
Publicado: (2020)

FMRP, a multifunctional RNA-binding protein in quest of a new identity
por: Khandjian, Edouard W., et al.
Publicado: (2022)

Activation of CCL21-GPR174/CCR7 on cardiac fibroblasts underlies myocardial ischemia/reperfusion injury
por: Meng, Xiao-Wen, et al.
Publicado: (2022)

Association of ANA, a Member of the Antiproliferative Tob Family Proteins, with a Cafl Component of the CCR4 Transcriptional Regulatory Complex
por: Yoshida, Yutaka, et al.
Publicado: (2001)

Toxicogenomics in non-mammalian species—Editorial
por: Stürzenbaum, Stephen, et al.
Publicado: (2012)

Toxicological Effects of Cadmium on Mammalian Testis
por: Zhu, Qiqi, et al.
Publicado: (2020)

Epigenetic alteration and microRNA dysregulation in cancer
por: Suzuki, Hiromu, et al.
Publicado: (2013)

The Regulatory Properties of the Ccr4–Not Complex
por: Chalabi Hagkarim, Nafiseh, et al.
Publicado: (2020)

Functions and Interactions of Mammalian KDM5 Demethylases
por: Pavlenko, Egor, et al.
Publicado: (2022)

Target-capture full-length double-stranded cDNA long-read sequencing through Nanopore revealed novel intron retention in patient with tuberous sclerosis complex
por: Ura, Hiroki, et al.
Publicado: (2023)

Massively Parallel Reporter Assays in Cultured Mammalian Cells
por: Melnikov, Alexandre, et al.
Publicado: (2014)

Impact of Growth Hormone-Related Mutations on Mammalian Aging
por: Bartke, Andrzej, et al.
Publicado: (2018)

Building a Mammalian Retina: An Eye on Chromatin Structure
por: Daghsni, Marwa, et al.
Publicado: (2021)

Cost-Effective Mapping of Genetic Interactions in Mammalian Cells
por: Khan, Arshad H., et al.
Publicado: (2021)

Epigenetic silencing of a multifunctional plant stress regulator
por: Zander, Mark, et al.
Publicado: (2019)

On the Physiological and Psychological Phenomena of Dreams and Apparitions
Publicado: (1856)

Cannot write session to /tmp/vufind_sessions/sess_0204eein5l7okgv79nogltmuak