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Loss of N-terminal Acetylation Suppresses A Prion Phenotype By Modulating Global Protein Folding
N-terminal acetylation is among the most ubiquitous of protein modifications in eukaryotes. While loss of N-terminal acetylation is associated with many abnormalities, the molecular basis of these effects is known for only a few cases, where acetylation of single factors has been linked to binding a...
Autores principales: | Holmes, William M., Mannakee, Brian K., Gutenkunst, Ryan N., Serio, Tricia R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140192/ https://www.ncbi.nlm.nih.gov/pubmed/25023910 http://dx.doi.org/10.1038/ncomms5383 |
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