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Molecular Pathogenesis of Polymerase Gamma–Related Neurodegeneration

OBJECTIVE: Polymerase gamma (POLG) mutations are a common cause of mitochondrial disease and have also been linked to neurodegeneration and aging. We studied the molecular mechanisms underlying POLG-related neurodegeneration using postmortem tissue from a large number of patients. METHODS: Clinical...

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Detalles Bibliográficos
Autores principales:	Tzoulis, Charalampos, Tran, Gia Tuong, Coxhead, Jonathan, Bertelsen, Bjørn, Lilleng, Peer K, Balafkan, Novin, Payne, Brendan, Miletic, Hrvoje, Chinnery, Patrick F, Bindoff, Laurence A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140551/ https://www.ncbi.nlm.nih.gov/pubmed/24841123 http://dx.doi.org/10.1002/ana.24185

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