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Specificity and Affinity Quantification of Flexible Recognition from Underlying Energy Landscape Topography
Flexibility in biomolecular recognition is essential and critical for many cellular activities. Flexible recognition often leads to moderate affinity but high specificity, in contradiction with the conventional wisdom that high affinity and high specificity are coupled. Furthermore, quantitative und...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140643/ https://www.ncbi.nlm.nih.gov/pubmed/25144525 http://dx.doi.org/10.1371/journal.pcbi.1003782 |