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Tracing the Evolution of Lineage-Specific Transcription Factor Binding Sites in a Birth-Death Framework
Changes in cis-regulatory element composition that result in novel patterns of gene expression are thought to be a major contributor to the evolution of lineage-specific traits. Although transcription factor binding events show substantial variation across species, most computational approaches to s...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140645/ https://www.ncbi.nlm.nih.gov/pubmed/25144359 http://dx.doi.org/10.1371/journal.pcbi.1003771 |