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Delineating the Importance of Serum Opsonins and the Bacterial Capsule in Affecting the Uptake and Killing of Burkholderia pseudomallei by Murine Neutrophils and Macrophages
Infection of susceptible hosts by the encapsulated Gram-negative bacterium Burkholderia pseudomallei (Bp) causes melioidosis, with septic patients attaining mortality rates ≥40%. Due to its high infectivity through inhalation and limited effective therapies, Bp is considered a potential bioweapon. T...
Autores principales: | Mulye, Minal, Bechill, Michael P., Grose, William, Ferreira, Viviana P., Lafontaine, Eric R., Wooten, R. Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140662/ https://www.ncbi.nlm.nih.gov/pubmed/25144195 http://dx.doi.org/10.1371/journal.pntd.0002988 |
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