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Elevated Levels of Dickkopf-1 Are Associated with β-Catenin Accumulation and Poor Prognosis in Patients with Chondrosarcoma

BACKGROUND: Dickkopf-1 (DKK1) is an antagonist of Wnt/β-catenin signaling implicated in tumorigenesis. However, the biological role of DKK1 and β-catenin involved in chondrosarcoma has not been sufficiently investigated. This study was designed to investigate the expression profiles of DKK1 and β-ca...

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Detalles Bibliográficos
Autores principales: Chen, Changbao, Zhou, Hua, Zhang, Xiaolin, Ma, Xinlong, Liu, Zhongjun, Liu, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140757/
https://www.ncbi.nlm.nih.gov/pubmed/25144498
http://dx.doi.org/10.1371/journal.pone.0105414