Cargando…

Elevated Levels of Dickkopf-1 Are Associated with β-Catenin Accumulation and Poor Prognosis in Patients with Chondrosarcoma

BACKGROUND: Dickkopf-1 (DKK1) is an antagonist of Wnt/β-catenin signaling implicated in tumorigenesis. However, the biological role of DKK1 and β-catenin involved in chondrosarcoma has not been sufficiently investigated. This study was designed to investigate the expression profiles of DKK1 and β-ca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Changbao, Zhou, Hua, Zhang, Xiaolin, Ma, Xinlong, Liu, Zhongjun, Liu, Xiaoguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140757/ https://www.ncbi.nlm.nih.gov/pubmed/25144498 http://dx.doi.org/10.1371/journal.pone.0105414

Ejemplares similares

Identification of ZNF704 as a Novel Oncogene and an Independent Prognostic Marker in Chondrosarcoma
por: Chen, Changbao, et al.
Publicado: (2021)

Dysregulation of Zinc Finger Protein 395 Contributes to the Pathogenesis of Chondrosarcoma
por: Chen, Changbao, et al.
Publicado: (2021)

Upregulation of miR-211 Promotes Chondrosarcoma Development via Targeting Tumor Suppressor VHL
por: Chen, Changbao, et al.
Publicado: (2020)

Wnt/β-Catenin Signaling Activation beyond Robust Nuclear β-Catenin Accumulation in Nondysplastic Barrett’s Esophagus: Regulation via Dickkopf-1()()
por: Lyros, Orestis, et al.
Publicado: (2015)

Aberrant activation of Wnt/β-catenin signaling drives proliferation of bone sarcoma cells
por: Chen, Changbao, et al.
Publicado: (2015)

High serum levels of Dickkopf-1 are associated with a poor prognosis in prostate cancer patients
por: Rachner, Tilman D, et al.
Publicado: (2014)

Serum Dickkopf-1 expression level positively correlates with a poor prognosis in breast cancer
por: Zhou, Shao-jie, et al.
Publicado: (2014)

Expression of Dickkopf-1 and Beta-Catenin Related to the Prognosis of Breast Cancer Patients with Triple Negative Phenotype
por: Xu, Wen-Huan, et al.
Publicado: (2012)

Elevated blood levels of Dickkopf‐1 are associated with acute infections
por: Mazon, Melody, et al.
Publicado: (2018)

RETRACTED ARTICLE: Dickkopf-1 contributes to hepatocellular carcinoma tumorigenesis by activating the Wnt/β-catenin signaling pathway
por: Zhang, Rui, et al.
Publicado: (2019)

Retraction Note: Dickkopf-1 contributes to hepatocellular carcinoma tumorigenesis by activating the Wnt/β-catenin signaling pathway
por: Zhang, Rui, et al.
Publicado: (2023)

BAG3 promotes chondrosarcoma progression by upregulating the expression of β-catenin
por: Shi, Huijuan, et al.
Publicado: (2018)

Correction: Expression of Dickkopf-1 and Beta-Catenin Related to the Prognosis of Breast Cancer Patients with Triple Negative Phenotype
Publicado: (2014)

Dickkopf-3 and β-catenin play opposite roles in the Wnt/β-catenin pathway during the abnormal subchondral bone formation of human knee osteoarthritis
por: Liang, Xuegang, et al.
Publicado: (2022)

Nuclear β-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer
por: Li, Xi-Qing, et al.
Publicado: (2013)

Downregulation of renal tubular Wnt/β-catenin signaling by Dickkopf-3 induces tubular cell death in proteinuric nephropathy
por: Wong, D W L, et al.
Publicado: (2016)

Elevated levels of Dickkopf-related protein 3 in seminal plasma of prostate cancer patients
por: Zenzmaier, Christoph, et al.
Publicado: (2011)

Prognostic value of Dickkopf-1 and ß-catenin expression in advanced gastric cancer
por: Hong, Soon Auck, et al.
Publicado: (2018)

Accumulation of Paneth Cells in Early Colorectal Adenomas Is Associated with Beta-Catenin Signaling and Poor Patient Prognosis
por: López-Arribillaga, Erika, et al.
Publicado: (2021)

Galectin-3 and β-catenin are associated with a poor prognosis in serous epithelial ovarian cancer
por: Liu, Yunyun, et al.
Publicado: (2018)

Elevated serum visfatin levels are associated with poor prognosis of hepatocellular carcinoma
por: Sun, Yifan, et al.
Publicado: (2017)

MiR-215, an activator of the CTNNBIP1/β-catenin pathway, is a marker of poor prognosis in human glioma
por: Tong, Yong-Qing, et al.
Publicado: (2015)

Elevated serum Dickkopf-1 is a biomarker for bone erosion in patients with psoriatic arthritis
por: Chung, Yukchiu, et al.
Publicado: (2021)

Inhibition of oleandrin on the proliferation show and invasion of osteosarcoma cells in vitro by suppressing Wnt/β-catenin signaling pathway
por: Ma, Yunlong, et al.
Publicado: (2015)

Combined detection of dickkopf-1 subtype classification autoantibodies as biomarkers for the diagnosis and prognosis of non-small cell lung cancer
por: Shen, Lei, et al.
Publicado: (2017)

MiR-543 promotes cell proliferation and metastasis of renal cell carcinoma by targeting Dickkopf 1 through the Wnt/β-catenin signaling pathway
por: Chen, Zhi-yuan, et al.
Publicado: (2018)

R-Spondin 1/Dickkopf-1/Beta-Catenin Machinery Is Involved in Testicular Embryonic Angiogenesis
por: Caruso, Maria, et al.
Publicado: (2015)

Elf3 drives β-catenin transactivation and associates with poor prognosis in colorectal cancer
por: Wang, J-L, et al.
Publicado: (2014)

Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β-catenin signalling and apoptosis regulation in breast cancer cells
por: Xiang, Tingxiu, et al.
Publicado: (2013)

β‐Catenin Accumulation and Mutation of Exon 3 of the β‐Catenin Gene in Hepatocellular Carcinoma
por: Kondo, Yutaka, et al.
Publicado: (1999)

Elevated plasma D-dimer levels are associated with the poor prognosis of critically ill children
por: Wang, Guan, et al.
Publicado: (2022)

SERPINB3 is associated with TGF-β1 and cytoplasmic β-catenin expression in hepatocellular carcinomas with poor prognosis
por: Turato, C, et al.
Publicado: (2014)

Dickkopf-1 Inhibition Reactivates Wnt/β-Catenin Signaling in Rhabdomyosarcoma, Induces Myogenic Markers In Vitro and Impairs Tumor Cell Survival In Vivo
por: Giralt, Irina, et al.
Publicado: (2021)

Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer
por: Aguilera, Óscar, et al.
Publicado: (2015)

Differential β-catenin expression levels are associated with morphological features and prognosis of colorectal cancer
por: GAO, ZHAO-HUA, et al.
Publicado: (2014)

Dickkopf Homolog 3 (DKK3) Plays a Crucial Role Upstream of WNT/β-CATENIN Signaling for Sertoli Cell Mediated Regulation of Spermatogenesis
por: Das, Deepika Sharma, et al.
Publicado: (2013)

miR-410 acts as an oncogene in colorectal cancer cells by targeting dickkopf-related protein 1 via the Wnt/β-catenin signaling pathway
por: Wang, Wei, et al.
Publicado: (2019)

Dickkopf-related protein 1, a new biomarker for local immune status and poor prognosis among patients with colorectal liver Oligometastases: a retrospective study
por: Sui, Qiaoqi, et al.
Publicado: (2019)

Loss of vinculin and membrane-bound β-catenin promotes metastasis and predicts poor prognosis in colorectal cancer
por: Li, Ting, et al.
Publicado: (2014)

Elevated pretreatment plasma D-dimer levels and platelet counts predict poor prognosis in pancreatic adenocarcinoma
por: Liu, Peng, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_rdufbrncbl184ghtn7srhfajr8