Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP

The presence of multiple (5–100) colorectal adenomas suggests an inherited predisposition, but the genetic aetiology of this phenotype is undetermined if patients test negative for Mendelian polyposis syndromes such as familial adenomatous polyposis (FAP) and MUTYH-associated polyposis (MAP). We inv...

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Detalles Bibliográficos
Autores principales: Cheng, Timothy H T, Gorman, Maggie, Martin, Lynn, Barclay, Ella, Casey, Graham, Saunders, Brian, Thomas, Huw, Clark, Sue, Tomlinson, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140766/
https://www.ncbi.nlm.nih.gov/pubmed/24801760
http://dx.doi.org/10.1038/ejhg.2014.74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140766/
https://www.ncbi.nlm.nih.gov/pubmed/24801760
http://dx.doi.org/10.1038/ejhg.2014.74

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